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目的 IBL 样 T淋巴瘤属高度恶性肿瘤 ,由于其细胞成份的多样性 ,病理组织学上很易误诊为良性病变。现将 9例报告如下。方法 全部病例做病理组织学及免疫组化(ABC法 )检测。结果 组织学上最显著的特征是血管旁胞浆淡染透明的透明细胞显著增生 ,2例呈现弥漫增生 ,7例呈现小灶状增生。小至中等大的异型核细胞散在于小灶状增生的透明细胞周围。免疫组化染色显示透明细胞及异型核的小、中型细胞均为 T细胞来源 ,其中 CD45 RO阳性例 10 0% ,CD43阳性例 77.8% ,CD3阳性例 6 6 .7%。结论 IBL样 T淋巴瘤的诊断最重要的组织学特征是在 AIL D背景上出现透明细胞的片状或小灶状增生。免疫组化染色有助于诊断
The purpose of IBL-like T-lymphoma is a highly malignant tumor, due to the diversity of its cellular components, histopathology is very easy to misdiagnose benign lesions. Now report the following 9 cases. Methods All cases were examined by histopathology and immunohistochemistry (ABC method). Results The most prominent histological feature was the obvious hyperplasia of the transparent cells with light cytoplasm, the diffuse hyperplasia in 2 cases and the small focal hyperplasia in 7 cases. Small to medium sized anaplastic nuclei scattered around the small focal hyperplasia of clear cells. Immunohistochemical staining showed that both small and medium-sized cells of both clear and abnormal nuclei were T-cell sources. Among them, 10% were positive for CD45 RO, 77.8% were positive for CD43, and 6.7% were positive for CD3. Conclusions The most important histological feature of the diagnosis of IBL-like T-lymphoma is lamellar or focal hyperplasia of clear cells on the AIL D background. Immunohistochemical staining helps to diagnose