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血管壁的损伤、脂类代谢的障碍对动脉硬化的发生具有重要的意义。而且免疫系统的活动及失调对血管壁损伤和脂类代谢障碍的发生均起一定作用,从而对动脉硬化的发病学研究开辟了新的领域。本文就此问题做一简要复习和讨论。 一、免疫性血管壁损伤及其在动脉硬化发病学中的作用:血管壁的损伤是动脉硬化发生和发展的一个重要因素,它不仅是引起动脉壁纤维性增厚的直接原因,而且是血浆脂质沉积在动脉内膜的一个重要的条件。
The damage of blood vessel wall and the obstacle of lipid metabolism are of great significance to the occurrence of atherosclerosis. And the immune system activity and disorders on the vascular wall injury and lipid metabolism disorders play a role, and thus the pathogenesis of atherosclerosis has opened up new areas. This article on this issue to do a brief review and discussion. First, the immune vascular wall injury and its role in the pathogenesis of atherosclerosis: vascular wall injury is an important factor in the occurrence and development of atherosclerosis, which is not only the direct cause of fibrous wall thickening caused by the artery, but also plasma Lipid deposition in the arterial intima of an important condition.