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本文报道口服抗菌药环丙氟哌酸的临床效果和安全性,以及本品与标准疗法治疗泌尿系,呼吸系以及皮肤和皮肤结构感染作对照、双盲比较。方法 2236例感染患者中,有2203例可用于安全性分析,1676例患者中,有1652例可用于疗效评价。患者口服环丙氟哌酸250mg、500mg 或750mg片剂,大多数患者每日用量500~1500mg,无并发症泌尿系感染的常用量为每12小时250mg,其他感染用量为每12小时500或750mg。用于评价疗效的治疗期为3~231天(平均10天),72%患者用药7~14天。疗效评价对照与无对照研究的联合结
This article reports the oral antibacterial drug ciprofloxacin clinical efficacy and safety, as well as the goods and standard therapy for urinary tract, respiratory system and skin and skin structure infection control, double-blind comparison. Methods Of 2236 infected patients, 2203 were available for safety analysis and 1652 of 1676 patients were eligible for efficacy evaluation. Patients oral ciprofloxacin 250mg, 500mg or 750mg tablets, most patients daily dose of 500 ~ 1500mg, no complications Urinary tract infections commonly used dose of 250mg every 12 hours, the other with the amount of infection every 12 or 500 or 750mg . The duration of treatment used to evaluate efficacy was 3 to 231 days (an average of 10 days), and 72% of patients treated for 7 to 14 days. Efficacy Evaluation Controlled and Uncontrolled Joint Study