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目的 :探讨补充锌 +维生素D +钙剂治疗佝偻病的效果。方法 :随机分为 3组 ,每组各 5 3例。对照组给予常规治疗 (即维生素D +钙剂 ) ,治疗 1组先给予锌治疗 1个月后 +常规治疗 ,治疗 2组同时给予锌 +常规治疗。 3个月为 1疗程。治疗前后检测血清微量元素及骨碱性磷酸酶 (BALP)等项目。结果 :治疗 1、2组疗效好于对照组 ,差异非常显著 (P <0 0 1) ;治疗1组疗效好于治疗 2组 ,差异有显著性 (P <0 0 5 )。结论 :治疗大多数伴低锌的佝偻病先补锌 1个月 ,再加常规治疗 ,疗效更佳。
Objective: To investigate the effect of zinc supplementation + vitamin D + calcium treatment of rickets. Methods: Randomly divided into 3 groups, each of 53 cases. Control group was given conventional treatment (ie, vitamin D + calcium), treatment group 1 was given zinc treatment for 1 month after conventional treatment, and treatment group 2 was given zinc + conventional treatment at the same time. 3 months for a course of treatment. Serum trace elements and bone alkaline phosphatase (BALP) were detected before and after treatment. Results: The curative effect of treatment group 1 and 2 was better than that of control group (P <0.01). The curative effect of treatment group 1 was better than that of treatment group 2 (P <0.05). Conclusion: The treatment of most rickets with low zinc first zinc supplementation for 1 month, coupled with conventional treatment, the effect is better.