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目的探讨654-2胸腔注射治疗结核性渗出性胸膜炎临床疗效。方法选取2014年6月-2016年6月我院收治的结核性渗出性胸膜炎患者60例,随机分为治疗组和对照组,各30例。对照组采用综合疗法;治疗组在综合疗法的基础上胸腔注射654-2,每次10-30mg,每周用药2次。比较两组患者用药两周后的临床疗效。结果两组患者用药两周后,治疗组显效26例(86.67%)有效4例(13.33%),总有效率为100%;对照组显效8例(26.67%),有效18例(60.00%),总有效率为86.67%,治疗组显效率及总有效率均明显高于对照组,比较差异具有统计学意义(P<0.05)。结论 654-2胸腔注射具有胸腔积液吸收快,症状消失快的优点,且操作简单,副作用不大,可作为结核性渗出性胸膜炎的综合治疗措施之一,在临床推广使用。
Objective To investigate the clinical efficacy of 654-2 pleural injection in the treatment of tuberculous exudative pleurisy. Methods Sixty patients with tuberculous exudative pleurisy admitted in our hospital from June 2014 to June 2016 were randomly divided into treatment group and control group, with 30 cases in each group. The control group was treated by combination therapy. The treatment group was injected with 654-2 thorax, 10-30mg each time, on the basis of comprehensive therapy twice a week. Two groups of patients after two weeks of clinical efficacy. Results Two weeks after treatment, 26 cases (86.67%) were effective in treatment group and 4 cases (13.33%) in total effective rate. The total effective rate was 100% in control group, 8 cases (26.67%) in control group and 18 cases (60.00% , The total effective rate was 86.67%. The markedly effective rate and total effective rate of the treatment group were significantly higher than that of the control group, the difference was statistically significant (P <0.05). Conclusions 654-2 pleural cavity injection has the advantages of rapid absorption of pleural effusion and rapid disappearance of symptoms, and is simple to operate and has few side effects. It can be used as a comprehensive treatment for tuberculous exudative pleurisy in clinic.