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目的：研究卡他林（Ｃａｔａｌｉｎ）滴眼液在兔眼角膜、虹膜、晶体、巩膜、房水和玻璃体组织中不同时间的分布，为评价滴眼液在内眼病治疗上的意义提供依据。方法：卡他林经１３１Ｉ标记，在滴入兔眼后０５、１、２、４和６小时测定兔眼各组织的１３１Ⅰ每分钟计数率（ＣＰＭ）。结果：经分析表明兔眼房水在２小时内药物浓度最高，但２小时之后迅速下降。晶体和玻璃体中药物浓度较低，并且变化不大，在不同的测定时间滴进晶体中的卡他林药水仅为０１１％～０４４％。结论：卡他林滴眼液容易通过角膜进入房水，难以进入晶体
OBJECTIVE: To study the distribution of Catalin eye drops in cornea, iris, lens, sclera, aqueous humor and vitreous tissue of rabbits at different times, and to provide basis for evaluating the significance of eye drops in the treatment of endophthalmitis. Methods: Catharantine 131I labeled with rabbit eye at 0.5 1, 2, 4 and 6 hours after the determination of the rabbit’s eye tissue count rate of 131I (CPM). Results: The analysis showed that rabbit aqueous humor in two hours the highest drug concentration, but after 2 hours decreased rapidly. The concentration of drug in crystal and vitreous was lower and did not change much. The amount of cataritine dropping into the crystal was only 0.11% -0.44% at different time. Conclusion: Cathartane eye drops easily enter the aqueous humor through the cornea, making it difficult to enter the lens