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目的探讨子宫内膜间质肿瘤的临床、病理及其多成分分化特点、鉴别诊断和预后。方法回顾性分析2011年3月至2012年3月期间34例子宫内膜间质肿瘤患者的临床病理资料。重点分析患者的临床、病理、合并症、鉴别诊断及预后情况。结果不同类型肿瘤均有部分病例伴多成分分化,(17例伴平滑肌分化、8例伴性索样分化、1例伴纤维分化、1例伴纤维粘液样分化、1例伴上皮样分化,其中6例同时伴两种分化成分)。34例中有6例伴发子宫平滑肌瘤(其中2例同时伴发腺瘤样瘤,1例伴发高分化子宫内膜腺癌)。结论不同类型子宫内膜间质肿瘤均可伴发多成分分化及其他类型肿瘤,具备多样性病理形态特征,肿瘤有无浸润及肿瘤细胞异型程度、核分裂象数量是确定本瘤性质的必备条件。
Objective To investigate the clinical, pathological and multi-component differentiation characteristics, differential diagnosis and prognosis of endometrial stromal tumors. Methods The clinical data of 34 patients with endometrial stromal tumors from March 2011 to March 2012 were retrospectively analyzed. Focus on analysis of patients with clinical, pathological, complications, differential diagnosis and prognosis. Results There were some cases with multi-component differentiation in different types of tumors (17 with smooth muscle differentiation, 8 with cord-like differentiation, 1 with fibrosis, 1 with fibromyxoid differentiation and 1 with epithelial-like differentiation 6 cases accompanied by two kinds of differentiation components). Six of the 34 patients had uterine leiomyomas (two of them were accompanied by adenomatous tumors and one was associated with highly differentiated endometrial adenocarcinoma). Conclusion Different types of endometrial stromal tumors may be associated with multiple component differentiation and other types of tumors, with a diversity of pathological features, with or without tumor invasion and tumor cell abnormalities, the number of mitotic figures is necessary to determine the nature of the tumor .