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目的:了解无锡市出生缺陷发生情况,为制定有效干预措施提供依据。方法:回顾性分析2008年无锡市出生缺陷监测资料。结果:2008年无锡市出生缺陷发生率为6.46‰,城市高于农村,本地高于外地,第一产高于第二产及以上;出生缺陷儿的性别、发生季节和产母年龄无明显差异;出生缺陷前5位依次为肢体畸形、唇腭裂、先天性心脏病、耳部畸形、神经管畸形,占总出生缺陷近2/3,其中多指(趾)、先天性心脏病、唇腭裂、外耳畸形、唇裂占总出生缺陷的52.07%。结论:出生缺陷发生率不断降低,出生缺陷监测质量不断提高。应重点针对前5位出生缺陷疾病寻找突破口,实施有效的三级预防措施,降低出生缺陷发生率。
Objective: To understand the occurrence of birth defects in Wuxi and provide the basis for making effective interventions. Methods: A retrospective analysis of birth defects monitoring data in Wuxi in 2008. Results: The incidence of birth defects in Wuxi was 6.46 ‰ in 2008, higher in urban areas than in rural areas, higher in local areas than in second-generation areas and above, and no significant difference in gender, occurrence season and mother-birth age ; The top five birth defects were limb deformity, cleft lip and palate, congenital heart disease, ear deformity and neural tube defects, accounting for nearly 2/3 of the total number of birth defects. Among them, multiple fingers, congenital heart disease, cleft lip and palate , Outer ear deformity, cleft lip accounted for 52.07% of the total birth defects. Conclusions: The incidence of birth defects continues to decline, and the quality of birth defects monitoring continues to improve. Should focus on the first 5 birth defects in the search for a breakthrough, the implementation of effective tertiary prevention measures to reduce the incidence of birth defects.