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目的:研究探讨米索前列醇素以及米非司酮对于终止妊娠的临床效果,并对其并发症的发生率进行探讨,为临床终止妊娠提供理论参考依据。方法:对我院自2011年11月至2012年11月收治的80例自愿终止妊娠妇女的临床资料进行回顾性分析。将其平均分为两组,研究组和对照组,每组40例。研究组40例自愿终止妊娠妇女对其采用米索前列醇以及米非司酮终止其妊娠;对照组40例自愿终止妊娠妇女直接对其采用清宫术而不使用任何终止妊娠的药物。对比两组自愿终止妊娠妇女的临床疗效、阴道出血量、妊娠物排除的时间以及两组患者的手术后不良反应。评价米索前列醇素以及米非司酮配合清宫手术对于终止妊娠的临床效果。结果:两组患者对比,研究组妇女终止妊娠总有效率为97.5%,而对照组妇女终止妊娠总有效率为75.5%,研究组总有效率显著高于对照组,结果具有统计学意义(P<0.05)。研究组患者的阴道出血量、妊娠物排除的时间以及手术后并发症均优于对照组,结果具有统计学意义(P<0.05)。结论:米索前列醇以及米非司酮终止妊娠的临床效果优异,且并发症发生率低,阴道出血量少,妊娠物排除时间也较短,减少了患者的痛苦,值得广大医务工作者在临床上广泛使用。
Objective: To study the clinical effect of misoprostol and mifepristone on termination of pregnancy, and to explore the incidence of its complications, providing a theoretical reference for clinical termination of pregnancy. Methods: A retrospective analysis was performed on the clinical data of 80 women who voluntarily terminate pregnancy treated in our hospital from November 2011 to November 2012. The average was divided into two groups, study group and control group, 40 cases in each group. In the study group, 40 women who voluntarily terminate the pregnancy terminated their pregnancy with misoprostol and mifepristone. In the control group, 40 women who voluntarily terminate pregnancy adopted the curettage without any termination of pregnancy. The clinical efficacy, vaginal bleeding volume, time of exclusion of pregnancy and postoperative adverse reactions in two groups were compared between two groups of women who voluntarily terminated pregnancy. To evaluate the clinical effect of misoprostol and mifepristone combined with surgery for termination of pregnancy. Results: Compared with the control group, the total effective rate of termination of pregnancy was 97.5% in study group and 75.5% in control group, the total effective rate in study group was significantly higher than that in control group (P <0.05). The vaginal bleeding volume, time of exclusion of pregnancy and postoperative complications in the study group were better than those in the control group, with statistical significance (P <0.05). Conclusion: The clinical effect of misoprostol and mifepristone termination of pregnancy is excellent, and the incidence of complications is low, vaginal bleeding less, the exclusion of pregnancy time is shorter, reducing the patient’s pain, it is worth the majority of medical workers in Widely used clinically.