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慢性活动性肝炎(CAH)是指临床、生化和组织学上具有反复或持续存在的进行性肝内炎症和坏死特征的慢性肝病,有演变成为肝硬化的倾向。 本病可由多种病因引起,目前尚未充分了解,较公认的有:肝炎病毒的感染、自身免疫性疾病的肝脏损害、药物中毒或过敏。偶然肝豆状核变性的患者可以有类似CAH的临床和其他表现。有些CAH病例与酒精中毒有关。也有一些病例起因不明。在多种病因中,以病毒性肝炎为最多见,一般所说的CAH即指由于肝炎病毒(多为乙型肝炎
Chronic active hepatitis (CAH) refers to chronic liver disease characterized by progressive or persistent progressive intrahepatic inflammation and necrosis clinically, biochemically and histologically, and the tendency to develop cirrhosis. The disease can be caused by a variety of causes, is not yet fully understood, more recognized are: hepatitis virus infection, autoimmune diseases, liver damage, drug poisoning or allergies. Patients with incidental Wilson’s disease may have clinical and other manifestations similar to CAH. Some cases of CAH and alcoholism. There are also some cases of unknown origin. In a variety of causes, the most common viral hepatitis, generally referred to as CAH refers to the hepatitis virus (mostly hepatitis B