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本文对遵义地区43例鼻咽、鼻腔恶性淋巴瘤的临床病理及免疫学表型进行了研究,结果显示:全部病例均为弥漫型,无1例滤泡型。组织学类型以多形细胞性淋巴瘤为主,共33例(包括小细胞型13例,中多形15例,大多形5例),占767%。用UCHL-1、CD20和Mac387等多种单克隆抗体进行免疫表型研究,显示T细胞淋巴瘤37例(86%),B细胞淋巴瘤4例(9.3%),无1例组织细胞性淋巴瘤。鼻咽部T.B淋巴瘤比例为20:2,鼻腔为16:2。临床上,男女发病为人3:1,平均年龄41岁,55.8%的病例为高度恶性。此外还讨论了该病的发病率、诊断和鉴别诊断。
In this paper, 43 cases of nasopharyngeal and nasal malignant lymphoma in Zunyi were studied clinically, pathologically and immunologically. The results showed that all the cases were diffuse and none had follicular type. Histological type of pleomorphic lymphoma-based, a total of 33 cases (including 13 cases of small cell type, 15 cases of polymorphism, 5 cases of mostly shape), accounting for 767%. Immunophenotyping with a variety of monoclonal antibodies such as UCHL-1, CD20 and Mac387 showed that 37 (86%) T-cell lymphomas and 4 (9.3%) B-cell lymphomas Sexual lymphoma. Nasopharyngeal T. B lymphoma ratio of 20: 2, nasal cavity is 16: 2. Clinically, the incidence of men and women were 3: 1, mean age 41 years, 55.8% of the cases were highly malignant. Also discussed the incidence of the disease, diagnosis and differential diagnosis.