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胰岛素依赖型糖尿病患者的血糖控制程度,极受胰岛素从皮下组织吸收入血液的速率影响。作者最近观察了皮下血流和胰岛素吸收的相互关系。在吸烟所致周围血管收缩期间可影响胰岛素的吸收,作者检验了这个假说。9例有酮病倾向的胰岛素依赖型糖尿病患者,6女3男,年龄22～62(平均35±13)岁,糖尿病史3～17(平均8±6)年,胰岛素每天用量为32～46(平均38±6)U。全部患者体重均在标准体重±10%以内,均无神经病或肾病的
The degree of glycemic control in patients with insulin-dependent diabetes is greatly influenced by the rate at which insulin is absorbed into the blood from the subcutaneous tissue. The authors recently observed the relationship between subcutaneous blood flow and insulin absorption. The authors test this hypothesis by influencing insulin absorption during peripheral vasoconstriction induced by smoking. Nine patients with ketosis tended to have insulin-dependent diabetes mellitus, 6 males and 3 males, ranging in age from 22 to 62 (mean 35 ± 13) years and had a history of diabetes from 3 to 17 (mean, 8 ± 6) years. The daily dosage of insulin was 32 to 46 (Average 38 ± 6) U. All patients were within the standard weight of ± 10%, no neuropathy or nephropathy