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应用单向免疫扩散法测定了３０例正常儿童和５３例婴幼儿肺炎血浆纤维连结蛋白（Ｆｉｂｒｏｎｅｔｉｎ，Ｆｎ）含量。结果表明，肺炎患儿血浆Ｆｎ水平下降，与正常组比较有显著差异（Ｐ＜０．０５）；Ｆｎ水平与疾病的严重程度有关，重症肺炎组血浆Ｆｎ水平明显低于轻型肺炎组（Ｐ＜０．０５），表明Ｆｎ是肺炎病理生理过程中的重要炎性介质。
The contents of Fibronectin (Fn) in 30 normal children and 53 infants with pneumonia were measured by one-way immunodiffusion. The results showed that plasma Fn levels in children with pneumonia decreased significantly compared with the normal group (P <0.05). The level of Fn was related to the severity of the disease. The level of plasma Fn in severe pneumonia group was significantly lower than that in the mild pneumonia group (P < 0.05), indicating that Fn is an important inflammatory mediator in the pathophysiology of pneumonia.