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为了解重庆市不同人群 BZD的滥用和依赖性发生情况及其相关因素 ,采用“人口学调查表”、“1 5种 BZD调查清单”、“药物滥用情况调查表”和 BDEPQ对重庆市三所市级综合医院的门诊病人 (综合组 ) ,市精神病医院住院病人 (精神组 ) ,市药物依赖治疗中心的住院戒毒者 (吸毒组 )以及一所市内中学的全部初、高中学生 (学生组 )共 2 40 0人进行了调查 ,并应用 Logistic回归法分析研究了影响 BZD滥用和依赖性形成的危险因素。结果发现 ,2 40 0人中有 1 2 84人使用过 BZD,占 5 4% ,其中精神病组、学生组、吸毒组和综合组的使用者和其百分率分别为 5 0 2人 ( 84% )、71人( 1 6 % )、5 2 8人 ( 99% )和 1 83人 ( 2 2 % ) ;依赖性形成分别为 2 6 7人 ( 5 3% )、8人 ( 1 1 % )、396人( 75 % )和 2 7人 ( 1 5 % )。 1 8个因素的多元Logistic回归分析显示 ,情绪烦躁、持续用药、超大剂量用药、不了解 BZD的副反应为 BZD依赖性形成最突出的危险因素。
To understand the incidence and related factors of abuse and dependence of BZD among different populations in Chongqing, the demographic and social status of BZD in Chongqing were analyzed using “Demographic Questionnaire,” “15 BZD Surveys,” “Substance Abuse Questionnaire” and “BDEPQ” Outpatients (general group) in city-level general hospitals, inpatients (mental group) in city mental hospitals, in-hospital drug addicts (drug addicts) in drug dependence treatment centers, and all junior and senior high school students in a municipal secondary school ) Were investigated. Logistic regression was used to analyze the risk factors that affect the abuse and dependence of BZD. As a result, 12 84 out of 240 people used BZD, accounting for 54% of the total. Among them, the percentage of users of the psychiatric group, the student group, the drug addiction group and the comprehensive group was 502 (84%), respectively , 71 (16%), 528 (99%) and 1 83 (22%) respectively; the dependent forms were 267 (53%), 8 (11%), 396 (75%) and 27 (15%). Multivariate Logistic regression analysis of 18 factors showed that irritability, continuous medication and over-large-dose medication did not understand the side effects of BZD as the most prominent risk factors for BZD-dependent formation.