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黄体期缺损定义为黄体的孕酮生成缺损,而雌激素生成功能似无损害。黄体期缺损的临床表现包括,不育症和反复一期流产。此缺陷是约3.5%不育症者的病因,而在作者的习惯性流产病例中,约35%有黄体缺乏症。本文综述黄体期缺损的诊断、发病机理和治疗。诊断:黄体功能不全的最有效的诊断方法是子宫内膜活检。虽然基础体温表可提醒对此病的怀疑,但不能作为确诊的工具。除非有明显的黄体功能缺损,体温表不能定量反映孕酮缺乏症,反之亦然。在黄体期,每天作尿孕二醇或血浆孕酮测定,可检出正常的和黄体期缺损的月经周期间的差异。然而,这些试验不实用于临床,因为月经周期中孕
Luteal phase defect is defined as luteal progesterone-induced defects, while estrogen-like function seems to be no damage. Clinical manifestations of luteal phase defects include infertility and recurrent abortion. This deficiency is the cause of about 3.5% infertility, and in the authors’ habitual abortion cases, about 35% have luteal deficiency. This article reviews the diagnosis, pathogenesis and treatment of luteal phase defects. Diagnosis: The most effective diagnostic method for luteal insufficiency is endometrial biopsy. Although the basic thermometer may remind the suspicion of the disease, but not as a diagnostic tool. Unless there is a significant loss of luteal function, the thermometer does not quantitatively reflect progesterone deficiency, and vice versa. In the luteal phase, daily urine pregnancy diol or plasma progesterone determination, normal and luteal phase defects can be detected during the menstrual cycle differences. However, these tests are not clinically useful because of pregnancy during the menstrual cycle