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目的探究脯氨酸肽酶在多囊卵巢综合症中的作用。方法选择在我院就诊的23例PCOS患者为观察组,同时选择25例女性为正常对照组。收集患者血清进行脯氨酸肽酶活性、TOS、TAS、OSI、LH、FSH、T和PRL的测量。结果观察组脯氨酸肽酶活性明显多于对照组;TOS和OSI在观察组中较对照组高,且有显著性差异(P<0.05)。观察组的LH、PRL和T激素均有明显的上升趋势,且有显著性差异(P<0.05)。结论 PCOS患者血清脯氨酸肽酶活性显著升高,结合TOS和OSI的升高提示PCOS患者可能会有动脉样硬化的不利事件发生。
Objective To investigate the role of prolyl peptidase in polycystic ovary syndrome. Methods Select 23 cases of PCOS patients treated in our hospital as the observation group, while 25 women were selected as the normal control group. Patient sera were collected for prolyl peptidase activity, measurements of TOS, TAS, OSI, LH, FSH, T and PRL. Results Proline peptidase activity in the observation group was significantly higher than that in the control group. TOS and OSI in the observation group were higher than those in the control group, and there was a significant difference (P <0.05). The LH, PRL and T hormones in the observation group all showed a significant upward trend, with significant difference (P <0.05). Conclusions Serum proline peptidase activity was significantly increased in patients with PCOS. Combined with the increase of TOS and OSI, it is suggested that there may be adverse events of arteriosclerosis in PCOS patients.