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目的:探究N端脑钠肽前体在川崎病合并冠状动脉病变患儿中的水平变化及临床意义。方法:选择本院2013年1月至2017年1月50例川崎病合并冠状动脉病变患者作为观察组(采用N端脑钠肽前体进行检测),再选择本院50例发热患者作为对照组(采用酶联荧光分析技术进行检测),对比两组患者临床指标水平情况。结果:观察组患者CRP、ESR、cTnT、NT-proBNP均高于对照组,P<0.05。结论:采用N端脑钠肽前体对川崎病合并冠状动脉病变患者进行检测,能够对其进行早期诊断,对诊断其水平变化具有重要意义。
Objective: To investigate the changes and clinical significance of N-terminal pro brain natriuretic peptide in children with Kawasaki disease and coronary artery disease. Methods: From January 2013 to January 2017, 50 patients with Kawasaki disease complicated with coronary artery disease were selected as the observation group (using N-terminal pro-brain natriuretic peptide), and 50 patients with fever in our hospital were selected as the control group (Using enzyme-linked fluorescence assay for detection), comparing the clinical indicators of two groups of patients. Results: The CRP, ESR, cTnT and NT-proBNP in the observation group were significantly higher than those in the control group (P <0.05). Conclusion: It is of great significance to diagnose the level of N-terminal pro-brain natriuretic peptide precursor in early diagnosis of Kawasaki disease complicated with coronary artery disease.