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目的探讨HBs Ag阳性患者行IVF-ET治疗对早期胚胎发育及妊娠结局的影响。方法选取在我院生殖中心接受常规黄体期长方案行体外受精-胚胎移植(IVF-ET)治疗的不孕不育夫妇,以夫妇双方至少一方血清HBs Ag检测结果为阳性的124对夫妇为实验组,以夫妇双方血清HBs Ag检测结果均为阴性的316对夫妇为对照组,回顾性分析两组间受精情况、早期胚胎发育情况及妊娠结局间差异。结果实验组和对照组组间年龄、不育年限、基础FSH、GN用量等基础情况均无统计学差异(P>0.05);两组间受精率、卵裂率、优质胚胎率、种植率、临床妊娠率也均无统计学差异(P>0.05)。结论 HBs Ag阳性患者行IVF-ET治疗对早期胚胎发育及妊娠结局均无显著性影响。
Objective To investigate the effect of IVF-ET on early embryo development and pregnancy outcomes in HBsAg-positive patients. Methods Infertile couples undergoing routine luteal phase long-term IVF-ET treatment in our reproductive center of our hospital were selected and 124 couples with positive results of serum HBsAg test on at least one side of the couple Group, 316 couples with negative serum HBsAg test results were used as the control group. The fertilization status, early embryo development and pregnancy outcome were retrospectively analyzed. Results There was no significant difference in the basic conditions such as age, years of infertility, basic FSH and GN among the experimental group and control group (P> 0.05). The fertilization rate, cleavage rate, quality embryo rate, implantation rate, Clinical pregnancy rates were also no significant difference (P> 0.05). Conclusion IVF-ET treatment in HBsAg-positive patients has no significant effect on early embryo development and pregnancy outcome.