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１９７５年Ａｗａｓｔｈｉ证明硒是人体的必需微量元素之后，关于硒的生物学效应研究，有关硒在人体营养和健康方面的作用，有了更进一步的深入了解。已知缺硒与心血管病、肿瘤、肝脏疾病、恶性营养不良等多种疾病有关，在我国已证实和地方病（克山病、大骨节病）的发生有密切
After Awasthi proved that selenium was an essential trace element in human body in 1975, further study on the biological effects of selenium on the role of selenium in human nutrition and health has been conducted. It is known that selenium deficiency is associated with many diseases such as cardiovascular diseases, tumors, liver diseases and malignant malnutrition. It has been confirmed in our country that it is closely related to endemic diseases (Keshan disease and Kashin-Beck disease)