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目的 :探究宫外孕保守治疗中米非司酮与甲氨蝶呤治疗的临床效果。方法 :基于本院自2013年7月-2015年7月期间收治的50例宫外孕患者的临床资料,按照临床治疗方式的不同,随机的将这50例患者分为观察组(采用米非司酮+甲氨蝶呤治疗)和对照组(单纯的采用甲氨蝶呤治疗),两组各25例,观察比较两组患者的临床疗效以及并发症发生情况。结果 :观察组25例宫外孕患者临床治疗总有效92%明显的高于对照组25例宫外孕患者临床疗治疗总有效率68%(P<0.05),具有统计学意义;观察组25例宫外孕患者的并发症(腹痛、阴道流血、肝肾功能损伤、骨髓抑制等)发生率28%明显的低于对照组25例宫外孕患者的并发症发生率56%(P<0.05),具有统计学意义。结论 :在宫外孕保守治疗中,给予患者米非司酮+甲氨蝶呤治疗,能够有效的降低并发症发生率,全面的提升临床治疗效果。
Objective: To investigate the clinical efficacy of mifepristone and methotrexate in the conservative treatment of ectopic pregnancy. Methods: Based on the clinical data of 50 patients with ectopic pregnancy admitted to our hospital from July 2013 to July 2015, 50 patients were randomly divided into observation group (treated with mifepristone + Methotrexate treatment) and control group (simple use of methotrexate treatment), two groups of 25 cases, observed and compared the clinical efficacy and complications of two groups of patients. Results: The total effective rate of clinical treatment in 25 cases of ectopic pregnancy in observation group was significantly higher than that of control group (25%) (P <0.05), and that of 25 cases of ectopic pregnancy in observation group was significantly higher than that of control group Complications (abdominal pain, vaginal bleeding, liver and kidney dysfunction, bone marrow suppression, etc.) the incidence of 28% was significantly lower than the control group of 25 cases of ectopic pregnancy complication rate of 56% (P <0.05), with statistical significance. Conclusion: In the conservative treatment of ectopic pregnancy, patients given mifepristone + methotrexate treatment, can effectively reduce the incidence of complications, and comprehensively enhance the clinical treatment effect.