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目的探讨在肾脏疾病诊断中使用血清视黄醇结合蛋白的应用价值。方法选取我院2010年8月~2013年4月收治的69例肾脏疾病患者,检测肾功能损伤患者血清视黄醇结合蛋白的表达。分析各组患者血清视黄醇结合蛋白表达水平的差异,同时选择60例健康查体者为对照组。结果无论哪一种肾病患者,其血液中的RBP含量均与对照组之间存在一定程度的差异;慢性肾衰、肾病综合症、糖尿病肾病、慢性肾小球肾炎患者Cr浓度、UREA浓度、UA数据均明显高于对照组。结论血清视黄醇结合蛋白是评价肾脏疾病的良好指标之一,可作为临床诊断肾脏疾病的参考指标进行临床检测。
Objective To investigate the value of serum retinol binding protein in the diagnosis of renal disease. Methods Sixty-nine patients with renal disease admitted from August 2010 to April 2013 in our hospital were enrolled in this study. Serum retinol binding protein was detected in patients with renal dysfunction. The difference of serum retinol binding protein expression levels in each group was analyzed. At the same time, 60 healthy people were selected as the control group. Results No matter what kind of nephropathy patients, the RBP levels in the blood and the control group there is a certain degree of difference; chronic renal failure, nephrotic syndrome, diabetic nephropathy, chronic glomerulonephritis patients Cr concentration, UREA concentration, UA Data were significantly higher than the control group. Conclusion Serum retinol binding protein is one of the good indicators to evaluate the renal disease, which can be used as a reference for clinical diagnosis of kidney disease.