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近年来,有关糖尿病免疫异常的报告日益增多。本文作者认为,幼年型胰岛亲依赖性糖尿病(以下简称JOD)患者中存在着免疫学方面的异常,并与HLA有关。另外,与免疫异常有关的抑制性T细胞(以下简称s细胞)也引起了注意。作者对JOD患者s细胞的机能进行了检测。 JOD患者10例,2例成熟期起病的年轻糖尿病(MODY)患者,4例胰岛素依赖性成人型糖尿病患者,3例全身性红斑狼疮(SLE)患者;14例健康成人(年龄22—
In recent years, reports of abnormal immune responses to diabetes have been increasing. The authors believe that there are immunological abnormalities in juvenile islet-dependent diabetes mellitus (hereinafter referred to as JOD) and are associated with HLA. In addition, immunosuppression-related suppressor T cells (hereinafter referred to as s cells) also attracted attention. The authors tested s-cell function in JOD patients. 10 cases of JOD, 2 cases of MODY, 4 cases of insulin-dependent adult diabetic and 3 cases of systemic lupus erythematosus (SLE); 14 healthy adults (22-