Effect of rifampicin pre- and post-treatment on rotenone-induced dopaminergic neuronal apoptosis and

• 作 者: Yuanlin Sun Guohua Zhang Jie X
• 机 构: DepartmentofNeurology,BlanchetteRockefellerNeurosciencesInstitute
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2010年2期
• 基金项目: the Natural Science Foundation of Guangdong Province, No. 04009355＊, Science and Technology Planning Project of Guandong Province, China, 05B33801003＊

BACKGROUND: Rifampicin inhibits the formation of α-synuclein multimer and protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyritine (MPTP)-induced PC12 cell apoptosis.OBJECTIVE: To compare the effect of rifampicin pre-and post-treatment on tyrosine hy