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Background: Assessment of body composition may be of interest when the nutriti onal status of infants is evaluated but is often difficult since simple and vali d methods are lacking. With appropriate validation, measurements based on skinfo ld thickness (SFT) may be useful for this purpose. Aims: To evaluate the potenti al of a published met- hod, based on measurements of SFT, to assess total body fat (TBF) of infants; and to calculate the fat content of adipose tissue (AT) in infants using previou sly published information regarding AT volume and total body water. Subjects and methods: Forty-five full-term infants and eight infants born in gestational w eeks 31-33 were studied at a postnatal age of 4-131 and 44-75 d, respectively . The body water dilution method was used to obtain reference estimates of TBF ( TBF-BWD). Results: In full-term infants, TBF assessed using the skinfold metho d (TBF-SFT) minus TBF-BWD was 1.5±10.8%(mean±2SD). Furthermore, TBF-SFT mi nus TBFBWD (%, y) was correlated (P < 0.0001) with the average of TBF-SFT and TBF-BWD (%, x), showing that TBF-SFT was too high in lean infants and too low in infants with more TBF. In the full-term infants, AT contained 0.68±0.14 g fat/ml. In the premature infants, TBF-SFT(%), TBF-BWD (%) and the AT fat con tent were similar to the corresponding figures in nine full-term newborns. Conc lusion: The results indicate that the SFT method produced inaccurate and biased estimates of TBF in infants. A considerable variation between infants regarding their AT fat content may be an important reason for these findings.
Background: Assessment of body composition may be of interest when the nutriti onal status of infants is evaluated but is often tried since simple and vali d methods are lacking. With appropriate validation, measurements based on skinfo ld thickness (SFT) may be useful for this purpose. Aims: To evaluate the potenti al of a published met- hod, based on measurements of SFT, to assess total body fat (TBF) of infants; and to calculate the fat content of adipose tissue (AT) in infants using previou sly published information regarding AT volume and total body water. Subjects and methods: Forty-five full-term infants and eight infants born in gestational w eeks 31-33 were studied at a postnatal age of 4-131 and 44-75 d, respectively. The Body water dilution method was used to obtain reference estimates of TBF (TBF-BWD). Results: In full-term infants, TBF assessed using the skinfold metho d (TBF-SFT) minus TBF-BWD was 1.5 ± 10.8% ± 2SD). Further, TBF-SFT mi nus TBFBWD (%, y) was correlated (P <0.0001) with the average of TBF-SFT and TBF-BWD (%, x), showing that TBF-SFT was too high in lean infants and too low in infants with more TBF. AT contained 0.68 ± 0.14 g fat / ml. In the premature infants, TBF-SFT (%), TBF-BWD (%) and the AT fat con tent were similar to the corresponding figures in nine full-term newborns. Conc lusion: The results indicate that the SFT method produced inaccurate and biased estimates of TBF in infants. A considerable variation between infants regarding their AT fat content may be an important reason for these findings.