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我院以Vit K_3与红霉素联用,使其胃肠道反应消失或减轻。本组共48例,男27例,女21例;~1岁6例,~3岁10例,~7岁14例,~14岁18例。患儿均对红霉素有反应,出现不同程度腹痛伴恶心30例,呕吐14例。滴注部位痛9例。红霉素用量按20~30mg/kg给予,配制溶液浓度为1/500~1000,开始单用红霉素,当滴注出现反应,再将VitK_3加入红霉素溶液中同时静滴,剂量按1~2mg/kg,最大用量每次达40mg。一般加
Vit K_3 in our hospital with erythromycin, gastrointestinal reactions disappear or reduce. The group of 48 patients, 27 males and 21 females; 1 year old in 6 cases, ~ 3 years in 10 cases, ~ 7 years in 14 cases, ~ 14 years in 18 cases. All children had erythromycin reaction, with varying degrees of abdominal pain with nausea in 30 cases, vomiting in 14 cases. Instillation site pain in 9 cases. Erythromycin dosage by 20 ~ 30mg / kg to give the solution concentration of 1/500 ~ 1000, began to use erythromycin, when the drop appeared reaction, then add VitK_3 intravenous infusion of erythromycin solution, the dose by 1 ~ 2mg / kg, the maximum amount of up to 40mg each time. General plus