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目的探讨本地区中枢性协调障碍(central coordination disturbance,CCD)患儿的高危因素,为临床预防和早期干预提供依据。方法对265例CCD患儿和270例正常婴儿的相关基本信息和病史资料进行回顾性整理,对相关因素进行统计分析。结果 265例CCD患儿中,232例(87.55%)存在一种或多种高危因素,其中产前因素38.78%,产时因素34.11%,产后因素27.11%,平均每例患儿计2.1个高危因素,高危因素构成比中前五位依次为病理性黄疸和剖宫产、多次人流、缺氧缺血性脑病、母高龄、早产及/或LB;含1种高危因素的两组儿童差异无统计学意义,含2种或多种以上(≥3种)高危因素的两组儿童差异均有统计学意义。结论多种高危因素可导致CCD的发生,产前因素占主体因素。做好孕期保健监测、加强产儿科诊治急救技术、加强新生儿保健和婴儿保健,预防和阻断可预防的危险因素,对高危儿早期发现、早期干预,能有效降低CCD的发生率。
Objective To explore the risk factors of children with central coordination disturbance (CCD) in the region and provide the basis for clinical prevention and early intervention. Methods The basic information and medical records of 265 children with CCD and 270 normal infants were retrospectively analyzed, and the related factors were statistically analyzed. Results Among the 265 cases of CCD, 232 (87.55%) had one or more risk factors, of which 38.78% were prenatal, 34.11% for labor, 27.11% for postpartum, and 2.1 for each case Factors, risk factors constitute the ratio of the top five followed by pathological jaundice and cesarean section, multiple abortion, hypoxic-ischemic encephalopathy, mother of age, premature birth and / or LB; with a high risk of two groups of children differences There was no significant difference between the two groups of children with two or more risk factors (≥3). Conclusion A variety of risk factors can lead to the occurrence of CCD, prenatal factors accounted for the main factors. To do a good job in monitoring of pregnancy health, strengthen pediatric diagnosis and treatment of emergency first aid technology, strengthen neonatal and infant health care, prevent and block preventable risk factors, high-risk infants early detection and early intervention can effectively reduce the incidence of CCD.