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探讨Ｐｔｅｎ／ＭＭＡＣ１／Ｔｅｐ１蛋白在不同分化程度的脑肿瘤组织中的表达。［方法］应用免疫组化技术检测３０例 脑胶质细胞瘤和１５例脑膜瘤Ｐｔｅｎ／ＭＭＡＣ１／Ｔｅｐ１蛋白表达。［结果］脑胶质细胞瘤组织中Ｐｔｅｎ／ＭＭＡＣ１／Ｔｅｐ１蛋白表达阳性率为 ５３．３３％，脑膜瘤组织中Ｐｔｅｎ／ＭＭＡＣ１／Ｔｅｐ１蛋白表达阳性率为９３．３３％，两者差异有显著性（Ｐ＜０．０１）。［结论］Ｐｔｅｎ／ＭＭＡＣ１／Ｔｅｐ１ 蛋白丢失与脑胶质瘤的分化程度密切相关。
To investigate the expression of Pten / MMAC1 / Tep1 in brain tumor tissues with different degrees of differentiation. [Methods] Immunohistochemical technique was used to detect the expression of Pten / MMAC1 / Tep1 protein in 30 cases of glioma and 15 cases of meningioma. [Results] The positive rate of Pten / MMAC1 / Tep1 protein in brain glioma was 53.33%, and the positive rate of Pten / MMAC1 / Tep1 protein in meningioma was 93.33%. There was a significant difference between the two groups (P <0.01). [Conclusion] The loss of Pten / MMAC1 / Tep1 protein is closely related to the differentiation of glioma.