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对纤溶动态图在纤溶药效研究中应用的可行性进行了考察,结果表明:纤溶动态图测定参数中,相对凝固程度(RCE)、平衡时间(BT)、完全溶解时间(CDT)和最大溶解速度(MDR)与纤溶作用密切相关,并呈明显的剂量依赖性(P<0.05)。提示:纤溶动态图是一简便有效的体外纤溶药效研究方法。
The feasibility of application of fibrinolytic activity in the study of fibrinolytic effect was investigated. The results showed that relative solidification (RCE), equilibrium time (BT), complete dissolution time (CDT) And maximum dissolution rate (MDR) and fibrinolysis are closely related, and showed a significant dose-dependent (P <0.05). Tip: fibrinolytic dynamic map is a simple and effective in vitro fibrinolytic efficacy of research methods.