Evaluation, treatment, and surveillance of neurogenic detrusor overactivity in spinal cord injury pa

• 作 者: Ali Alsulihem Jacques Corcos
• 机 构: Department of Urology, Jewish General Hospital, McGill University, 3755 C?te-Sainte-Catherine Road,
• 出 处: 神经免疫与神经炎症（英文版）
• 发表日期: 2019年11期
• 关键词: Spinal cord injury neurogenic lower urinary tract dysfunction neurogenic bladder

Neurogenic detrusor overactivity is a common urodynamic finding in patients with supra-sacral spinal cord injury. Early evaluation, stepped management, and close follow-up reduce the risk of upper urinary tract deterioration, renal failure and incontinence. In this article, we aim to outline the modern pathway of the management of this complex disease. Evaluation of patients with history, physical examination, renal function assessment, cystoscopy, and urodynamic study are essential. Management of neurogenic detrusor overactivity with adequate bladder drainage, medical therapy, intradetrusor botulinum injections, and surgery can be offered in a stepwise manner. Follow-up after specific interventions should be done in a timely fashion to detect treatment response and to avoid complications of poorly managed neurogenic detrusor overactivity.