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目的探讨左快诺孕酮宫内节育系统(曼月乐)对子宫腺肌病患者月经异常和痛经的临床治疗效果。方法对36例子宫腺肌病患者放置曼月乐后进行12个月的4次随访,在1、3、6、12月时,对痛经程度、月经量及子宫体积变化情况对比分析。结果患者痛经评分、月经量逐月下降,在1个月变化不明显,3、6、12个月时,较放置前有明显下降(P<0.05或P<0.01);12个月时子宫体积较放置前有明显缩小(P<0.05)。结论曼月乐是治疗子宫腺肌病的一种安全有效的方法。
Objective To investigate the clinical efficacy of Zuetuo-Progesterone intrauterine system (Mirena) in patients with dysfunctional menstruation and dysmenorrhea in patients with adenomyosis. Methods Thirty-six patients with adenomyosis were followed up for 12 months with Mirena. At 1, 3, 6 and 12 months, the changes of dysmenorrhea, menstrual flow and uterine volume were compared. Results Dysmenorrhea scores decreased month by month in patients with dysmenorrhea, with no significant changes at 1 month. The levels of dysmenorrhea were significantly decreased at 3 months, 6 months and 12 months (P <0.05 or P <0.01) Compared with place before significantly reduced (P <0.05). Conclusion Mirena is a safe and effective method for the treatment of adenomyosis.