论文部分内容阅读
目的 :探讨磁导航系统在非ST抬高型急性冠脉综合征(non-ST-elevation acute coronary syndromes,NSTE-ACS)介入治疗中应用的可行性和安全性。方法:连续选择接受磁导航辅助介入治疗的中-高危NSTE-ACS患者37例,分别记录靶病变特征、导丝通过病变的时间、X线暴露时间、造影剂用量和相关并发症。用STATA9.2软件进行数据分析。结果:磁导航引导治疗靶病变37处,其中A/B1型病变7处、B2型病变17处、C型病变13处。术前靶病变平均狭窄程度和长度分别为(88.07±8.33)%和(27.08±8.98)mm。在磁导航指引下,磁导丝顺利通过36处靶病变,病变通过率为97.3%;失败1例,磁导丝未能通过1处次全闭塞伴严重钙化病变。磁导丝通过靶病变的平均时间为(82.0±67.9)s,其中A/B1、B2、C型病变的通过时间分别为(34.7±4.5)s、(61.0±14.7)s和(134.8±92.6)s;X线平均暴露时间(62.6±57.6)s,A/B1、B2、C型病变的暴露时间分别为(22.3±4.7)s、(45.2±14.5)s、(106.9±78.4)s;造影剂平均用量(6.3±4.6)ml,A/B1、B2、C型病变用量分别为(2.7±0.7)ml、(5.1±2.6)ml、(9.8±5.7)ml。介入术中未出现与应用导丝相关的冠状动脉夹层、穿孔等并发症;术后未发生心血管复合事件。结论:磁导航系统应用于NSTE-ACS的辅助介入治疗有可行性,磁导丝病变通过率高、安全性好。
Objective: To investigate the feasibility and safety of magnetic navigation system in interventional therapy of non-ST-elevation acute coronary syndromes (NSTE-ACS). Methods: Thirty-seven consecutive patients with moderate-high risk NSTE-ACS receiving magnetic-magnetic-assisted interventional therapy were enrolled in this study. The characteristics of the target lesion, the time of the lesion passing through the lesion, the time of X-ray exposure, the dosage of contrast medium and the related complications were recorded. Data analysis with STATA9.2 software. Results: Magnetically guided treatment of 37 target lesions, including A / B1 lesions 7, B2 lesions 17, C lesions 13. The mean stenosis and length of preoperative target lesions were (88.07 ± 8.33)% and (27.08 ± 8.98) mm, respectively. Under the guidance of magnetic navigation, the magnetic guide wire passed 36 target lesions successfully, the pass rate of the lesions was 97.3%; in 1 failed, the magnetic guide wire failed the sub-total occlusion with severe calcification lesions. The average time for the magnetic flux to pass the target lesion was (82.0 ± 67.9) s, and the passage time of A / B1, B2 and C lesions were (34.7 ± 4.5) s, (61.0 ± 14.7) s and (134.8 ± 92.6) ) s; the average exposure time of X ray was (62.6 ± 57.6) s, the exposure time of A / B1, B2 and C lesions were (22.3 ± 4.7) s, (45.2 ± 14.5) s and (106.9 ± 78.4) The average dosage of contrast medium was (6.3 ± 4.6) ml. The dosage of A / B1, B2 and C were (2.7 ± 0.7) ml, (5.1 ± 2.6) ml and (9.8 ± 5.7) ml respectively. There was no complications such as coronary artery dissection and perforation associated with application of guide wire during interventional procedure. No postoperative cardiovascular events occurred. Conclusion: Magnetic guidance system is feasible in the interventional therapy of NSTE-ACS. The permeable rate of the guide wire is high and the safety is good.