Deregulated Polycomb repressive complex 2 (PRC2) is intimately involved in tumorigenesis and progression,making it an invaluable target for epigenetic cancer th
Lysosomes are the terminal organelles of the autophagic-endocytic pathway and play a key role in the degradation of autophagic contents.We previously reported t
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a novel strategy for cancer therapy,but only two inhibitors of NAMPT (FK866 and CHS828) have pro