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目的:分析我院抗菌药物在国家基本药物制度和抗菌药物专项整治活动实施前后的利用情况,评估我院抗菌药物品种、用药特点、使用合理性受政策利导的的变化情况。方法:对我院2010-2011年抗菌药物用药频度(DDDs)、日均费用(DDC)、药物利用指数(DUI)、金额/DDDs排序位次比、平均治疗日数(ATD)进行统计、分析。结果:随着国家基本药物制度实施,基本药物在我院抗菌药物DDDs排名前10位的抗菌药物中比重增加,DDC在几元至30多元之间,金额/DDDs排序位次比偏高;我院抗菌药物DUI小于1和大于1的情况普遍存在,用药不足和用药过量的情况均不容乐观,ATD与药品说明书的规定疗程比较亦有出入。结论:国家基本药物制度推动了基本药物在医院的使用,基本药物在DDC、金额/DDDs排序位次比上具有显著优势,降低了患者的经济负担;通过抗菌药物分级管理制度,将DUI和ATD配合抗菌药物专项整治活动中对抗菌药物临床应用的点评,可及时发现医师用药方面的弊端,促进临床合理使用抗菌药物。
OBJECTIVE: To analyze the utilization of antibacterial drugs in our hospital before and after the implementation of the national essential drug system and antimicrobial special rectification activities, to evaluate the changes of antimicrobial drug varieties, drug use characteristics and rational use of drugs in our hospital. Methods: The data of DDDs, DDC, DUI, DD / DDDs, and the average number of treatment days (ATD) in our hospital from 2010 to 2011 were analyzed statistically . Results: With the implementation of the national essential drug system, the proportion of essential drugs in the top 10 antimicrobial drug DDDs in our hospital increased. DDC was between a few yuan and more than 30 yuan, and the order of the amount / DDDs was higher; Hospital antimicrobial drugs DUI less than 1 and more than 1 prevalence of under-medication and overdose conditions are not optimistic, ATD and drug prescriptions prescribed treatment is also different. Conclusion: The national essential drug system has promoted the use of essential medicines in hospitals. The basic medicines have significant advantages in terms of DDC, the order of the amount / DDDs, reducing the economic burden on patients. Through the classification system of antimicrobial agents, DUI and ATD With the special rectification activities of antimicrobial drugs, the clinical application of antimicrobial drugs reviews can be found in time the drawbacks of physician medication to promote the rational use of antimicrobial agents.