Interleukin-10 Is Expressed in HepG2.2.15 Cells and Regulated by STAT1 Pathway

• 作 者: 刘敏 郝友华 丁红晖 杨东亮 陆蒙吉
• 机 构: DivisionofClinicalImmunology,ExperimentalMedicineCenter,DepartmentofMicrobiology,InstituteofVirology
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2011年5期
• 关键词: 白细胞介素10 HepG2细胞 抗病毒治疗 肝癌细胞 蛋白表达 PCR分析 ELISA DNA水平 hepatoma cellinterleukin-10hep
• 基金项目: supported by grants from the National Major Science and Technology Special Project for Infectious Diseases of China （No. 2008ZX10002-011）

This study investigated the expression profiles of IL-10 gene in three human hepatoma cell lines including Huh7, HepG2, and HepG2 transfected with a plasmid containing hepatitis B virus (HBV) named HepG2.2.15. RT-PCR analysis demonstrated that IL-10 messa