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目的探讨奥美拉唑与泮托拉唑治疗上消化道出血的成本-效果分析。方法将上消化道出血患者168例随机分为2组,每组84例。实验组给予泮托拉唑治疗,对照组给予奥美拉唑治疗,比较2组疗效、药物成本-效果及不良反应。结果实验组患者治疗后,总有效率为97.62%,对照组患者治疗后,总有效率为96.43%,两组患者临床疗效相近,差值对比无统计学意义(P>0,05),但实验组治疗成本和成本-效果比都低于对照组。结论奥美拉唑与泮托拉唑治疗上消化道出血的疗效相似,但泮托拉唑的成本-效果更佳。
Objective To investigate the cost-effectiveness of omeprazole and pantoprazole in the treatment of upper gastrointestinal bleeding. Methods 168 cases of upper gastrointestinal bleeding were randomly divided into two groups, 84 cases in each group. The experimental group was treated with pantoprazole, while the control group was treated with omeprazole. The curative effect, drug cost-effectiveness and adverse reactions of the two groups were compared. Results After treatment, the total effective rate was 97.62% in the experimental group and 96.43% in the control group. The clinical efficacy of the two groups was similar, but the differences were not statistically significant (P> 0.05) The experimental group cost of treatment and cost-effectiveness ratio are lower than the control group. Conclusions The efficacy of omeprazole and pantoprazole in the treatment of upper gastrointestinal bleeding is similar, but the cost-effectiveness of pantoprazole is better.