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放射造影剂检查有时可导致急性肾功能衰竭 (ARF),血管造影术的危险性(发生率0.5%)似比静脉尿路造影术或计算机断层术(发生率0.15%)高;口服法胆囊造影术的并发症较少。通常表现为造影后12~48小时出现少尿,一般在5天内尿量又开始增加,血清肌酐到7天时达到最高峰。大多数患者肌酐可恢复正常,许多轻微病人可能未被查出。老年患者最普通的临床症状是水潴留。原有严重肾功能衰竭患者可能需要处理商钾血症,偶需作透析。肾脏损害的机理未明,血管注射的三碘化合剂与血浆相比是高渗的(1,350~1,800mmol/L),引起肾脏损害最可能的原因是肾脏血流的改变及肾小球滤过率减少。渗透性较低的新造影剂(例如 Iocar-
Radiographic contrast agents can sometimes lead to acute renal failure (ARF), angiography risk (0.5% incidence) than intravenous urography or computed tomography (incidence of 0.15%) higher; oral gallbladder surgery Complications less surgery. Usually manifested 12-48 hours after angiography oliguria, urine volume began to increase in 5 days, serum creatinine reached the peak of 7 days. Creatinine in most patients returns to normal, and many minor patients may not be detected. The most common clinical symptom of elderly patients is water retention. The original patients with severe renal failure may need to deal with hyperkalemia, occasionally for dialysis. The mechanism of renal damage is unknown. The intravascular injection of triiodide is hypertonic (1,350 to 1,800 mmol / L) compared to plasma. The most likely cause of kidney damage is renal blood flow changes and glomerular filtration rate cut back. Low permeability new contrast agents (such as Iocar-