New means to monitor the effect of glucocorticoid therapy in children

• 作 者: Hanne Rintamki Harri M Salo O
• 机 构: DivisionofGastroenterology,ImmuneResponseUnit
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年9期
• 关键词: Glucocorticoid-induced tumor NECROSIS factor receptor FOXP3 Inflammatory BOWEL d
• 基金项目: Supported by The Finnish Cultural Foundation,the Finnish Pediatric Research Foundation,the Pivikki and Sakari Sohlberg Foundation,and the Orion Research Foundation

AIM:To study the individual effects of glucocorticoid (GC) therapy on the state ofimmune activation in patient serum.METHODS:We developed a novel assay in which the effect of corticosteroid-treated patient serum on healthy donor peripheral blood mononucle