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实验结果显示,兔慢性化脓性骨髓炎模型的红细胞C_3b受体花环率、兔疫复合物花环率及血清溶菌酶含量均明显低于正常水平。用中药消炎止痛汤治疗后,模兔的红细胞免疫粘附活性及血清溶菌酶含量迅速恢复正常,分别为8.66±1.47(造模前为8.86±1.69)及28.81±6.27(造模前为28.63±5.27)。认为:红细胞免疫功能及血清溶菌酶活力低下,是慢性化脓性骨髓炎经久难愈或反复发作的主要原因之一;消炎止痛汤治疗骨髓炎的作用与促进机体的免疫功能有关。
The experimental results showed that the red blood cell C_3b receptor rosette rate, rabbit epidemic complex rosette rate and serum lysozyme content in rabbits with chronic suppurative osteomyelitis were significantly lower than normal levels. After treatment with traditional Chinese medicine Xiaoyan Zhitong Decoction, the red blood cell immune adherence activity and serum lysozyme content of the rabbits quickly returned to normal, they were 8.66±1.47 (8.86±1.69 before modeling) and 28.81±6.27 (28.63± before modeling). 5.27). It is believed that the immune function of red blood cells and the low serum lysozyme activity are one of the main reasons for the long-lasting refractory or recurrent attack of chronic suppurative osteomyelitis; the effect of Xiaoyan Zhitong Decoction in treating osteomyelitis is related to the promotion of the body’s immune function.