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自从去年以来,在我国一些地区的家兔饲养群中发生了一种急性传染性疾病,病程短,死亡率高,濒死前体温升高1—2℃,稽留8—24小时。病死兔经解剖检查,主要病变是多种器官和组织出现(氵弥)散性或灶状出血。我们对病变器官如肝、肺、肾等的超薄切片曾作电子显微镜观察,发现在病变细胞的胞质中存在很多病毒样颗粒(图1)。张哲夫等也有相同的报道。为了弄清这种颗粒的性质,及其与家兔的这种传染性疾病确切的病因关系,本文报道我们在病毒的分离、纯化、鉴定和家兔感染的一些实
Since last year, there has been an acute infectious disease in rabbits in some areas of our country. The disease duration is short and the mortality rate is high. The body temperature before death is increased by 1-2 ° C, leaving a delay of 8-24 hours. Rabbit anatomical examination of the dead rabbits, the main lesion is a variety of organs and tissues appear (Mi Mi) diffuse or focal hemorrhage. We observed the ultrathin sections of diseased organs such as liver, lung, kidney, etc. and found that there were many virus-like particles in the cytoplasm of diseased cells (Fig. 1). Zhang Zhefu also reported the same. In order to clarify the nature of this pellet and its exact etiological relationship with this infectious disease in rabbits, we report some of the differences between the virus isolation, purification, identification, and infection in rabbits