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成人隐匿性自身免疫糖尿病(latent autoimmune diabetes inadults,LADA)是1993年被命名的成年起病、缓慢进展的自身免疫性1型糖尿病,约占临床2型糖尿病的10%～15%,其早期临床表现酷似2型糖尿病,但胰岛β细胞遭受缓慢免疫破坏而导致胰岛素缺乏。由于受检测手段的限制,该病极易被误诊为2型糖尿病而延误治疗,严重影响患者身心健康,造成巨大的社会及经济负担,已引起世界糖尿病学界的关注。中南大学湘雅二医院代谢内分泌研究所自1995年开始,在国家自然科学基金、卫生部青年科技人才基金、教育
Latent autoimmune diabetes in adults (LADA) is an adult onset, slow-growing autoimmune type 1 diabetes named 1993, accounting for about 10% to 15% of clinical type 2 diabetes. Its early clinical Performance resembles type 2 diabetes, but islet β cells suffer from slow immune destruction leading to insulin deficiency. Due to the limitations of testing methods, the disease can be easily misdiagnosed as type 2 diabetes and delayed treatment, seriously affecting the patient’s physical and mental health, resulting in a huge social and economic burden, which has aroused the concern of the world diabetes community. Second Xiangya Hospital of Central South University Institute of Metabolism and Endocrinology since 1995, the National Natural Science Foundation of China, the Ministry of Health Youth Science and Technology Talent Fund, education