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目的探讨多普勒超声(TCD)检查对海南地区原住居民后循环缺血(PCI)的诊断价值。方法选800例PCI患者及100例健康者,采用TCD及CT血管成像(CTA)检查,探查双侧大脑后动脉(PCA)、双侧椎动脉(VA)、基底动脉(BA)的峰值血流速度(Vs)、平均血流速度(Vm)、舒张末期血流速度(Vd),记录动脉搏动指数(PI)及频谱形态变化特征。结果研究组TCD检查管腔闭塞32条,轻度狭窄272条,中度狭窄96条,重度狭窄16条;双侧VA、PCA、BA的PI值及右侧VA、BA的Vs值显著高于对照组,双侧PCA的Vd值显著低于对照组(P<0.05);血流速度加快和减慢所占比例均显著高于对照组(P<0.05)。结论 TCD与CTA具有高度一致性,TCD检查能为PCI的诊断、病情评估、治疗和预后提供依据。
Objective To investigate the diagnostic value of Doppler ultrasound (TCD) in diagnosis of posterior circulation ischemia in Hainan. Methods Totally 800 patients with PCI and 100 healthy controls were enrolled in this study. TCD and CT angiography (CTA) were performed to detect peak blood flow of bilateral posterior cerebral artery (PCA), bilateral vertebral artery (VA) and basilar artery (BA) Vs, Vm, Vd, PI and spectral features were recorded. Results In the study group, there were 32 lumen obliteration, 272 mild stenosis, 96 moderate stenosis and 16 severe stenosis. The PI of bilateral VA, PCA and BA and Vs of right VA and BA were significantly higher than that of VA In the control group, the Vd value of bilateral PCA was significantly lower than that of the control group (P <0.05); the proportion of accelerated and slowed blood flow velocity was significantly higher than that of the control group (P <0.05). Conclusion TCD and CTA are highly consistent. TCD can provide the basis for the diagnosis, assessment, treatment and prognosis of PCI.