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目的探讨宫颈癌术前应用新辅助化疗的临床疗效。方法 68例宫颈癌术前采用2个疗程的新辅助化疗后进行手术,观察近期疗效。结果 68例患者化疗2个疗程后的临床总有效率为70.1%。经过术前辅助化疗后,进行广泛性子宫切除加盆腔淋巴结清扫手术,全部患者均顺利切除病灶。结论术前新辅助化疗对宫颈癌Ⅰb1~Ⅱb期患者治疗安全有效,可缩小肿瘤体积,提高手术切除率及疗效,进一步改善患者的生活质量。
Objective To investigate the clinical effect of neoadjuvant chemotherapy before cervical cancer. Methods 68 cases of cervical cancer preoperative use of two courses of neoadjuvant chemotherapy after surgery to observe the short-term efficacy. Results The total effective rate of 68 patients after two courses of chemotherapy was 70.1%. After preoperative adjuvant chemotherapy, extensive hysterectomy and pelvic lymph node dissection surgery, all patients were successfully removed lesions. Conclusion Preoperative neoadjuvant chemotherapy for patients with cervical cancer Ⅰb1 ~ Ⅱb safe and effective treatment, can reduce tumor size, improve surgical resection rate and efficacy, and further improve the quality of life of patients.