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目的分析左氧氟沙星药品不良反应(ADR)的发生情况,为临床合理用药提供参考。方法对55例左氧氟沙星ADR报告进行回顾性分析。结果左氧氟沙星ADR所累及的系统-器官主要为皮肤及其附件(49.1%),消化系统(20.0%)及用药部位损害(10.9%)。老年人为不良反应的高发人群。结论左氧氟沙星可引起多种不良反应,应加强其ADR监测,保障安全用药。
Objective To analyze the incidence of adverse drug reaction (ADR) of levofloxacin and provide reference for clinical rational drug use. Methods 55 cases of levofloxacin ADR report were retrospectively analyzed. Results The main organs and organs involved in levofloxacin ADR were skin and its appendages (49.1%), digestive system (20.0%) and drug-site lesions (10.9%). Elderly people are high risk groups for adverse reactions. Conclusion Levofloxacin can cause a variety of adverse reactions, should strengthen its ADR monitoring to ensure safe medication.