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Oddi’s括约肌运动功能不良是由于括约肌狭窄或功能紊乱所致的临床综合征。最典型的临床表现是胆囊切除术后反复发作的上腹部或右上腹部严重而稳定的疼痛 ,疼痛发作后肝功能异常 ,或有胆总管扩张 ,造影剂引流延迟。目前诊断方法虽多样 ,内镜测压术仍是临床诊断的金标准。内镜切开括约肌和肉毒杆菌素注射是治疗的重要措施 ,可使症状短期缓解。寻找新的安全、简便、有效、理想的检查治疗方法 ,仍是比较艰巨的任务。
Oddi’s sphincter dysfunction is a clinical syndrome due to sphincter stenosis or dysfunction. The most typical clinical manifestations of recurrent after cholecystectomy in the upper abdomen or upper right abdomen severe and stable pain, liver dysfunction after pain episodes, or have common bile duct dilatation, delayed drainage of contrast agent. Although the current diagnosis is diverse, endoscopic manometry is still the gold standard for clinical diagnosis. Endoscopic sphincter and botulinum toxin injection is an important measure of treatment, can short-term relief of symptoms. Looking for new safe, simple, effective and ideal examination and treatment methods, is still a more difficult task.