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目的探讨内分泌联合维生素D应用于晚期前列腺癌的治疗效果。方法将晚期前列腺癌患者40例,采用数字随机法将其分为对照组和研究组,每组各20例,对照组患者采用单纯内分泌治疗,研究组患者采用内分泌联合维生素D治疗,比较两组患者的临床治疗效果。结果研究组血清PSA控制的总有效率为84.4%,对照组血清PSA控制完全缓解和部分缓解的共有30例,总有效率为66.7%,实验组明显高于对照组,两组比较差异有统计学意义,P<0.05;研究组病灶的控制率为86.7%,对照组的肿瘤病灶控制率为71.1%,研究组明显高于对照组,两组比较差异有统计学意义,P<0.05。结论内分泌联合维生素D应用于晚期前列腺癌中具有良好的治疗效果,值得临床推广使用。
Objective To investigate the therapeutic effect of endocrine combined with vitamin D on advanced prostate cancer. Methods Forty patients with advanced prostate cancer were randomly divided into control group and study group, 20 cases in each group. Patients in control group were treated with endocrine therapy only. Endocrine combined with vitamin D was used in the study group. The clinical effect of the patient. Results The total effective rate of serum PSA control was 84.4% in the study group. The total effective rate was 66.7% in the control group with complete and partial remission of PSA control. The experimental group was significantly higher than the control group, and the difference was statistically significant P <0.05. The control rate of the study group was 86.7%, while that of the control group was 71.1%. The study group was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion Endocrine combined with vitamin D in the treatment of advanced prostate cancer has a good therapeutic effect and is worthy of clinical promotion.