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原发阴道癌占女性生殖道肿瘤的1~2%,是老年性疾病。近年报告,放疗有较高的治愈率,且复发率低。 1965~1981年间,Luke氏医学中心,Lutheran综合医院和Christ医院的肿瘤放疗科共收治32例原发阴道癌。年龄在38~90岁之间,60%超过60岁。最常见的症状是阴道出血和排液(71%)。组织学检查为鳞癌25例(78%),腺癌3例,恶性未分化癌4例。按FIGO分期标准Ⅰ期8例,Ⅱ期18例,Ⅲ期5例,Ⅳ期1例。病变累及阴道上1/3的19例,中1/3的2例,下1/3的6例,累及阴道2/3以上或全阴道的5例。除2例外,所有病人随访2~11年。Ⅰ期8例中7例采用腔内或组织间照射。腔内放疗用Manchester法或Fletcher的卵园形施用
Primary vaginal cancer accounts for 1 to 2% of female genital tract tumors, is a senile disease. In recent years, radiotherapy has a higher cure rate, and the recurrence rate is low. Between 1965 and 1981, 32 primary vaginal cancers were treated in the Oncology Department of Luke’s Medical Center, Lutheran General Hospital and Christ Hospital. The age of 38 to 90 years old, 60% over 60 years old. The most common symptoms are vaginal bleeding and drainage (71%). Histological examination was squamous cell carcinoma in 25 cases (78%), adenocarcinoma in 3 cases, malignant undifferentiated carcinoma in 4 cases. According to FIGO staging standard Ⅰ in 8 cases, Ⅱ in 18 cases, Ⅲ in 5 cases, Ⅳ in 1 case. Lesions involving the vagina on the 1/3 of 19 cases, 1/3 in 2 cases, 1/3 in 6 cases, involving the vagina more than 2/3 or all vagina in 5 cases. With the exception of 2 cases, all patients were followed up for 2 to 11 years. Seven cases of stage Ⅰ in 8 cases were treated with intracavitary or interstitial irradiation. Endoluminal radiotherapy with Manchester method or Fletcher oval-shaped application