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目的研究2型糖尿病合并非酒精性脂肪肝超声严重程度与尿微量白蛋白的关系。方法应用超声诊断2型糖尿病合并非酒精性脂肪肝及其严重程度,并比较其与尿微量白蛋白的关系。结果2型糖尿病合并非酒精性脂肪肝组的尿微量白蛋白及阳性率[(32.19±3.87)mg/L,35.1%]高于2型糖尿病不合并非酒精性脂肪肝组[(23.43±4.12)mg/L,9.2%],差异均有统计学意义(P<0.05)。2型糖尿病合并非酒精脂肪肝的超声下轻中重度三组尿微量白蛋白差异有统计学意义(P<0.05),且其严重程度与尿微量白蛋白的阳性率成正相关(Z=2.962,P=0.003<0.05)。结论 2型糖尿病合并非酒精性脂肪肝患者的严重程度与尿微量白蛋白存在着正相关关系,提示其严重程度可一定程度的预测糖尿病的微血管病变。
Objective To study the relationship between the severity of type 2 diabetes with non-alcoholic fatty liver and the severity of urinary microalbumin. Methods Ultrasonography was used to diagnose type 2 diabetes mellitus patients with non-alcoholic fatty liver and its severity, and to compare with urine microalbumin. Results The positive rate of urinary albumin in type 2 diabetic patients with nonalcoholic fatty liver disease was significantly higher than that in type 2 diabetic patients without alcoholic fatty liver [(32.19 ± 3.87) mg / L, 35.1% (23.43 ± 4.12) mg / L, 9.2%], the differences were statistically significant (P <0.05). There was a significant difference in urinary microalbuminuria between mild and moderate three groups of type 2 diabetes mellitus patients with nonalcoholic fatty liver disease (P <0.05), and its severity was positively correlated with the positive rate of urine microalbumin (Z = 2.962, P = 0.003 <0.05). Conclusions There is a positive correlation between the severity of type 2 diabetes mellitus and microalbuminuria in patients with non-alcoholic fatty liver disease, suggesting that its severity may predict the microangiopathy of diabetes to a certain extent.