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目的探讨静脉药物配置中心（PIVAS）对预防医院感染管理的有效方法，以控制静脉输液所致的医院感染。方法分析传统分散式的静脉药物配置环境带来的不安全因素，对PIVAS的洁净区采取一系列的消毒灭菌措施；对人流、物流及操作规程进行严格管理。结果 PIVAS有效地减少了医院感染的发生；增加了静脉输液的安全性，各项监测指标均达到国家规定标准。结论加强静脉药物配置中心各环节的质量管理，对提高医院感染管理水平和保障医疗安全具有重要意义。“,”Objective To explore the ef ective quality management in the pharmacy intravenous admixture services (PIVAS) to prevent the nosocomial infection, in order to control infection caused by intravenous infusion. Methods We analyzed the unsafe factors brought by traditional distributed intravenous drug preparation. We taken disinfection measurement and management of the staf , articles and operation criteria strictly. Results The high risk factors of nosocomial infection were revented, thus nosocomial infection was decreased ef ectively. And every supervision items had reached the government standards. Conclusion A series of practical management system and processes are built up to promote the management of nosocomial infection and to guarantee the quality of medical service.