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目的:探讨儿童甲状腺乳头状癌的临床病理特点、预后相关因素。方法:回顾性总结12例儿童甲状腺乳头状癌(≤14岁)的临床病理特征及预后。结果:本组12例经组织学检查证实为甲状腺乳头状癌,其中3例为术前穿刺诊断,全部行术中冰冻检查,12例均行手术切除治疗,手术时伴淋巴结转移者7例,被膜有浸润者5例。术后平均随访47.3个月,有5例复发,复发病例中2例伴肺转移,伴肺转移中有1死亡病例。结论:儿童甲状腺乳头状癌经手术治疗预后较好。术中病理冰冻切片诊断是确诊甲状腺乳头状癌的最佳方法。
Objective: To investigate the clinicopathological features and prognostic factors of papillary thyroid carcinoma in children. Methods: The clinicopathological features and prognosis of papillary thyroid carcinoma (≤14 years old) in 12 children were retrospectively reviewed. Results: The group of 12 cases confirmed by histological examination of thyroid papillary carcinoma, including 3 cases of preoperative biopsy, all intraoperative frozen check, 12 cases underwent surgical resection, surgery with lymph node metastasis in 7 cases, There are 5 cases of infiltration of the capsule. After an average follow-up of 47.3 months, 5 patients relapsed, 2 patients relapsed with pulmonary metastases, 1 patients with lung metastases. Conclusion: The prognosis of thyroid papillary carcinoma in children after surgery is good. Intraoperative frozen section diagnosis is the best way to diagnose papillary thyroid carcinoma.