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目的探讨某院住院患者多重耐药菌(MDRO)的临床分布及特征,为制定医院感染管理防控策略提供可靠依据。方法选择2011年1月-2012年12月该院101例多重耐药菌感染住院患者,按照美国临床实验室标准化委员会(NCCLS)推荐使用的表型确认试验进行超广谱β-内酰胺酶菌株的检测。结果 101例多重耐药菌感染患者中,大肠埃希菌检出例数最多,其次是金黄色葡萄球菌、阴沟肠杆菌、肺炎克雷伯菌发生耐药率均在10%以上。结论建立多重耐药菌管理制度,早期预防、早期干预、循证感控,可降低多重耐药菌医院感染的暴发和流行。
Objective To investigate the clinical distribution and characteristics of multiple drug-resistant bacteria (MDRO) in hospitalized patients in a hospital and provide a reliable basis for the prevention and control strategies of nosocomial infection. METHODS: From January 2011 to December 2012, 101 hospitalized patients with multidrug-resistant bacteria were enrolled. ESBLs-producing strains were selected according to the phenotypic confirmation test recommended by the American Clinical Laboratory Standardization Committee (NCCLS) The test. Results Among the 101 cases of multi-drug-resistant infections, the most cases of Escherichia coli were detected, followed by Staphylococcus aureus, Enterobacter cloacae and Klebsiella pneumoniae, all of which were over 10%. Conclusion The establishment of multidrug-resistant bacteria management system, early prevention, early intervention, evidence-based control can reduce the outbreak and epidemic of hospital-acquired multi-drug resistant bacteria.